Homocysteine is becoming increasingly familiar amongst the medical community, nutritionists and health writers, as scientific evidence continues to highlight the damaging effects that this compound exerts upon the cardiovascular system. It is considered to be a causative factor for heart disease, as it triggers arterial damage that may lead to heart attacks and strokes. A high homocysteine level is also a risk factor for blood clots in the veins. Research also suggests that high homocysteine levels are implicated in the development and progression of cognitive impairment, dementia and even Alzheimer's disease.
Homocysteine is made from protein in the diet. The amino acid, methionine is converted into homocysteine. In a well-nourished body, this is then converted either back into methionine or on into other harmless compounds. Unfortunately, many individuals are lacking the nutrients needed for these conversions and are left with potentially damaging levels of homocysteine in their blood.
Fortunately, the defence against homocysteine is simple and inexpensive. It is just a matter of ensuring an adequate intake of the vitamins B6, B12 and Folic acid. When there is adequate B6 in the diet, methionine is converted into the harmless compound cystathione. Both Folic acid and vitamin B12 donate methyl groups to homocysteine —a process that converts homocysteine back into methionine. Researchers have also found that a phytonutrient known as trimethylglycine (TMG) is also an effective methyl donor.
The vital nutrients needed to reduce homocysteine levels are:
- Vitamin B6
- Vitamin B12
- Folic Acid